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Lyrica found to be no better than placebo for sciatica

Posted: Fri Mar 31, 2017 3:31 pm
by Jason32
Thought I would post this here since many PN patients (myself included) have suffered with sciatica at some point: a randomized, double-blind, placebo-controlled study just published last week in The New England Journal of Medicine (arguably the most prestigious medical journal in the U.S.) showed Lyrica (Pregabalin) to be no better than a placebo for sciatica. Anecdotally, I know of no one who was helped with nerve pain by Lyrica. If it doesn't work for the sciatic nerve I very highly doubt it works for the pudendal. This is a good example of why I keep hammering on the need for randomized, controlled trials for PN treatments- especially PNE surgery.

The study can be found here:
http://www.nejm.org/doi/full/10.1056/NE ... tured_home&

It also received some mainstream news coverage:
http://www.reuters.com/article/us-healt ... SKBN16T32Q