Please help :(

[April]

Hi Balenul,

I've never heard about a connection between antidepressants and pn, and it seems to me to extremely unlikely, given my understanding of how the problem usually starts.

April

[Violet M]

There are people who say they developed PGAD after discontinuing an SSRI, or even from taking an SSRI. There hasn't been a lot of research on the topic. Here is one article.
https://link.springer.com/article/10.10 ... 20-00240-0

The question is, do some of these people actually have PGAD due to pudendal neuralgia or some other peripheral neuropathy with PGAD as their primary symptom, or does the SSRI somehow affect the brain and trigger PGAD. No one seems to know the relationship for sure. So while in some cases there seems to be a possible relationship between SSRI's and the development of PGAD, whether the PGAD is pudendal related isn't always known. So, I guess in that sense, we can't say for sure whether it is possible for SSRI's to cause pudendal neuralgia with PGAD as the only symptom. However, like April, I have never heard of anyone developing typical pudendal neuralgia (with pain) from taking SSRI's. There are people who develop PGAD who never took SSRI's and there are people who have many other symptoms of pudendal neuralgia along with PGAD. So, it's a complicated problem.

[Kibellboo]

Hi thought I'd weigh in. I've seen a few people in the antidepressant groups I've joined over the years that have pudendal neuralgia symptoms after taking or withdrawing from medication. It's not as common as the symptoms of interstitial cystitis that a lot of them get (sometimes even without PGAD), but I've definitely met quite a few people with the typical PN symptoms like burning, stinging, fullness, pain, etc alongside PGAD. AD induced PGAD and PN is usually temporary though and sometimes these symptoms can be acute and fade quickly. For me personally, my PN symptoms are like that, I will have them for maybe a month or 3 after a drug reaction and then PGAD just remains longer. Hope that helps at all, the effects of ADs are confusing.

Also for a small update I've found out that I have multiple chemical sensitivity syndrome ever since withdrawing from ADs back in 2018, and this explains why I keep getting retriggered by random chemicals so often even years later. I always know because the PN symptoms are one of the first to start before the rest.

[Violet M]

Thanks for posting that. I hadn't heard of multiple chemical sensitivty syndrome before.

This site has some good info about it. https://www.aafp.org/pubs/afp/issues/19 ... /p721.html

[Balenul]

Hi thought I'd weigh in. I've seen a few people in the antidepressant groups I've joined over the years that have pudendal neuralgia symptoms after taking or withdrawing from medication. It's not as common as the symptoms of interstitial cystitis that a lot of them get (sometimes even without PGAD), but I've definitely met quite a few people with the typical PN symptoms like burning, stinging, fullness, pain, etc alongside PGAD. AD induced PGAD and PN is usually temporary though and sometimes these symptoms can be acute and fade quickly. For me personally, my PN symptoms are like that, I will have them for maybe a month or 3 after a drug reaction and then PGAD just remains longer. Hope that helps at all, the effects of ADs are confusing.

Also for a small update I've found out that I have multiple chemical sensitivity syndrome ever since withdrawing from ADs back in 2018, and this explains why I keep getting retriggered by random chemicals so often even years later. I always know because the PN symptoms are one of the first to start before the rest.

I think somehow the Ssri / Snri damage the pelvic nerves .Problem is for some people is permanent i met some

[Balenul]

There are people who say they developed PGAD after discontinuing an SSRI, or even from taking an SSRI. There hasn't been a lot of research on the topic. Here is one article.
https://link.springer.com/article/10.10 ... 20-00240-0

The question is, do some of these people actually have PGAD due to pudendal neuralgia or some other peripheral neuropathy with PGAD as their primary symptom, or does the SSRI somehow affect the brain and trigger PGAD. No one seems to know the relationship for sure. So while in some cases there seems to be a possible relationship between SSRI's and the development of PGAD, whether the PGAD is pudendal related isn't always known. So, I guess in that sense, we can't say for sure whether it is possible for SSRI's to cause pudendal neuralgia with PGAD as the only symptom. However, like April, I have never heard of anyone developing typical pudendal neuralgia (with pain) from taking SSRI's. There are people who develop PGAD who never took SSRI's and there are people who have many other symptoms of pudendal neuralgia along with PGAD. So, it's a complicated problem.

I replyed to a older post on a Pgad thread.I really think Ssri Pgad is always related with pelvic floor Violet.Somehow they damage that area.Some say is dopamine that bring alot of blood there and give us Pgad but i think they also dmg the nerves temporary or even permanent.Imo Pgad from only neurotransmit imbalance only with no effect on pelvic floor don t exist.Lexapro helped your Pgad ? Why you had a entrapment and no imbalance.

[Violet M]

I don't know, Balenul. Theoretically it seems possible that SSRI's affect the seratonin levels not only in the brain but in the peripheral nerves, including the pelvic nerves. But I don't know if any studies have ever been done to determine that. I haven't heard of SSRI's affecting dopamine but I don't know for sure.