For the few weeks I have been waking up in horrible pain. It will last for 3-4 days at a level 9. I take Nucynta which does help normally. Is this normal to wake up at 3:00 am in pain. Today I have taken more meds than what is prescribe. I know I should not have but I am miserable.
Missyrg
No relief
Re: No relief
I often wake in the middle of the night with extreme spasms....going to the toilet doesnt always relieve this but I do find ice helps me take my mind off things....along with many other options like deep breathing and yoga relaxation...if its bad I turn on the tv to distract my mind for a while.
Taking meds is ok, so long as you stick to the guidelines and prescription levels.
Wouldnt it be nice to go to bed and sleep soundly!
Taking meds is ok, so long as you stick to the guidelines and prescription levels.
Wouldnt it be nice to go to bed and sleep soundly!
PNE started 2003 following Vaginal Hysterectomy, pelvic floor repair and right oophorectomy; eventually after many tests had BilateralTG surgery Nantes 2004; following this tried many other treatments including 7 day epidural, ketamin infusions to no avail; Trialed and was implanted with a Neurostimulator in 2007- Dr Van Buyten Belgium, this has enabled me to manage my pain much better.
Re: No relief
Missy, do you take anything else besides Nucynta?
When my PNE was bad I used to wake up all hours of the night so I know what you are saying. Are you taking anything to help you sleep? Sometimes even just benadryl can help you sleep more soundly -- although you have to be careful when mixing drugs not to depress the central nervous system to a dangerous level.
When my PNE was bad I used to wake up all hours of the night so I know what you are saying. Are you taking anything to help you sleep? Sometimes even just benadryl can help you sleep more soundly -- although you have to be careful when mixing drugs not to depress the central nervous system to a dangerous level.
PNE since 2002. Started from weightlifting. PNE surgery from Dr. Bautrant, Oct 2004. Pain now is usually a 0 and I can sit for hours on certain chairs. No longer take medication for PNE. Can work full time and do "The Firm" exercise program. 99% cured from PGAD. PNE surgery was right for me but it might not be for you. Do your research.
Re: No relief
Violet, can you explain more? Would taking tylenol pm with seratonin do terrible things? What would depressing the central nervous system to a dangerous level do? make you sleepy? make you die? pardon my complete ignorance here.although you have to be careful when mixing drugs not to depress the central nervous system to a dangerous level.
-straddle fall age 4-7 w/bleeding labia, tampons hurt in teens, papsmere started annoying pelvic 'tingling' & pne in 02
-obturator surgery w/ Filler in 05 (useless, created sciatic & plantar fascitis pain)
-TIR surgery w/ Bautrant in 08 and vestibulectomy in 08 in France (vest. removed pain w/intercourse, pain w/sitting increased post surgery)
-chronic fatigue & food allergies/migraines (gluten, milk) from pain meds in 08
-want a life back. I'm 34 w/8+ years of pain
-obturator surgery w/ Filler in 05 (useless, created sciatic & plantar fascitis pain)
-TIR surgery w/ Bautrant in 08 and vestibulectomy in 08 in France (vest. removed pain w/intercourse, pain w/sitting increased post surgery)
-chronic fatigue & food allergies/migraines (gluten, milk) from pain meds in 08
-want a life back. I'm 34 w/8+ years of pain
Re: No relief
PG, here is a quick synopsis of CNS depressants taken from this website: http://tinyurl.com/4m97dqr
I've highlighted the key point near the end of this summary. SSRI's are not on this list but benadryl which is in tylenol PM is a CNS depressant.
Central Nervous System Depressants
Definition
Central nervous system (CNS) depressants are drugs that can be used to slow down brain activity.
Purpose
CNS depressants may be prescribed by a physician to treat anxiety, muscle tension, pain, insomnia, acute stress reactions, panic attacks, and seizure disorders. In higher doses, some CNS depressants may be used as general anesthetics.
Description
Throughout history, humans have sought relief from anxiety and insomnia by using substances that depress brain activity and induce a drowsy or calming effect. CNS depressants include a wide range of drugs such as alcohol, narcotics, barbiturates (Amytal, Nembutal, Seconal), benzodiazepines (Ativan, Halcion, Librium, Valium, Xanax), chloral hydrate, and methaqualone (Quaaludes), as well as newer CNS depressants developed in the 1990s, such as Buspirone (Buspar) and Zolpidem (Ambien), which are thought to have the fewest side effects. Most CNS depressants activate a neurotransmitter called gamma-aminobutyric acid (GABA), which helps decrease brain activity. Street names for CNS depressants include Reds, Yellows, Blues, Ludes, Barbs, and Downers.
Precautions
Most CNS depressants have the potential to be physically and psychologically addictive. Alcohol is the most widely abused depressant. The body tends to develop tolerance for CNS depressants, and larger doses are needed to achieve the same effects. Withdrawal from some CNS depressants can be uncomfortable; for example, withdrawal from a depressant treating insomnia or anxiety can cause rebound insomnia or anxiety as the brain's activity bounces back after being suppressed. In some cases withdrawal can result in lifethreatening seizures. Generally, depressant withdrawal should be undertaken under a physician's supervision. Many physicians will reduce the depressant dosage gradually, to give the body time to adjust. Certain CNS depressants such as barbiturates are easy to overdose on, since there is a relatively small difference between the optimal dose and an overdose. A small miscalculation can lead to coma, slowed breathing, and death. CNS depressants should be administered to elderly individuals with care, as these individuals have a reduced ability to metabolize CNS depressants.
Side effects
Especially when taken in excess, CNS depressants can cause confusion and dizziness, and impair judgment, memory, intellectual performance, and motor coordination.
Interactions
CNS depressants should be used with other medications, such as antidepressant medications, only under a physician's supervision. Certain herbal remedies, such as Valerian and Kava, may dangerously exacerbate the effects of certain CNS depressants. Also, ingesting a combination of CNS depressants, such Valium and alcohol, for example, is not advised. When mixed together, CNS depressants tend to amplify each other's effects, which can cause severely reduced heart rate and even death.
I've highlighted the key point near the end of this summary. SSRI's are not on this list but benadryl which is in tylenol PM is a CNS depressant.
Central Nervous System Depressants
Definition
Central nervous system (CNS) depressants are drugs that can be used to slow down brain activity.
Purpose
CNS depressants may be prescribed by a physician to treat anxiety, muscle tension, pain, insomnia, acute stress reactions, panic attacks, and seizure disorders. In higher doses, some CNS depressants may be used as general anesthetics.
Description
Throughout history, humans have sought relief from anxiety and insomnia by using substances that depress brain activity and induce a drowsy or calming effect. CNS depressants include a wide range of drugs such as alcohol, narcotics, barbiturates (Amytal, Nembutal, Seconal), benzodiazepines (Ativan, Halcion, Librium, Valium, Xanax), chloral hydrate, and methaqualone (Quaaludes), as well as newer CNS depressants developed in the 1990s, such as Buspirone (Buspar) and Zolpidem (Ambien), which are thought to have the fewest side effects. Most CNS depressants activate a neurotransmitter called gamma-aminobutyric acid (GABA), which helps decrease brain activity. Street names for CNS depressants include Reds, Yellows, Blues, Ludes, Barbs, and Downers.
Precautions
Most CNS depressants have the potential to be physically and psychologically addictive. Alcohol is the most widely abused depressant. The body tends to develop tolerance for CNS depressants, and larger doses are needed to achieve the same effects. Withdrawal from some CNS depressants can be uncomfortable; for example, withdrawal from a depressant treating insomnia or anxiety can cause rebound insomnia or anxiety as the brain's activity bounces back after being suppressed. In some cases withdrawal can result in lifethreatening seizures. Generally, depressant withdrawal should be undertaken under a physician's supervision. Many physicians will reduce the depressant dosage gradually, to give the body time to adjust. Certain CNS depressants such as barbiturates are easy to overdose on, since there is a relatively small difference between the optimal dose and an overdose. A small miscalculation can lead to coma, slowed breathing, and death. CNS depressants should be administered to elderly individuals with care, as these individuals have a reduced ability to metabolize CNS depressants.
Side effects
Especially when taken in excess, CNS depressants can cause confusion and dizziness, and impair judgment, memory, intellectual performance, and motor coordination.
Interactions
CNS depressants should be used with other medications, such as antidepressant medications, only under a physician's supervision. Certain herbal remedies, such as Valerian and Kava, may dangerously exacerbate the effects of certain CNS depressants. Also, ingesting a combination of CNS depressants, such Valium and alcohol, for example, is not advised. When mixed together, CNS depressants tend to amplify each other's effects, which can cause severely reduced heart rate and even death.
PNE since 2002. Started from weightlifting. PNE surgery from Dr. Bautrant, Oct 2004. Pain now is usually a 0 and I can sit for hours on certain chairs. No longer take medication for PNE. Can work full time and do "The Firm" exercise program. 99% cured from PGAD. PNE surgery was right for me but it might not be for you. Do your research.
Re: No relief
PG, here is a quick synopsis of CNS depressants taken from this website: http://tinyurl.com/4m97dqr
I've highlighted the key point near the end of this summary. SSRI's are not on this list but might be considered somewhat of a CNS depressant as is benadryl which is in tylenol PM.
Central Nervous System Depressants
Definition
Central nervous system (CNS) depressants are drugs that can be used to slow down brain activity.
Purpose
CNS depressants may be prescribed by a physician to treat anxiety, muscle tension, pain, insomnia, acute stress reactions, panic attacks, and seizure disorders. In higher doses, some CNS depressants may be used as general anesthetics.
Description
Throughout history, humans have sought relief from anxiety and insomnia by using substances that depress brain activity and induce a drowsy or calming effect. CNS depressants include a wide range of drugs such as alcohol, narcotics, barbiturates (Amytal, Nembutal, Seconal), benzodiazepines (Ativan, Halcion, Librium, Valium, Xanax), chloral hydrate, and methaqualone (Quaaludes), as well as newer CNS depressants developed in the 1990s, such as Buspirone (Buspar) and Zolpidem (Ambien), which are thought to have the fewest side effects. Most CNS depressants activate a neurotransmitter called gamma-aminobutyric acid (GABA), which helps decrease brain activity. Street names for CNS depressants include Reds, Yellows, Blues, Ludes, Barbs, and Downers.
Precautions
Most CNS depressants have the potential to be physically and psychologically addictive. Alcohol is the most widely abused depressant. The body tends to develop tolerance for CNS depressants, and larger doses are needed to achieve the same effects. Withdrawal from some CNS depressants can be uncomfortable; for example, withdrawal from a depressant treating insomnia or anxiety can cause rebound insomnia or anxiety as the brain's activity bounces back after being suppressed. In some cases withdrawal can result in lifethreatening seizures. Generally, depressant withdrawal should be undertaken under a physician's supervision. Many physicians will reduce the depressant dosage gradually, to give the body time to adjust. Certain CNS depressants such as barbiturates are easy to overdose on, since there is a relatively small difference between the optimal dose and an overdose. A small miscalculation can lead to coma, slowed breathing, and death. CNS depressants should be administered to elderly individuals with care, as these individuals have a reduced ability to metabolize CNS depressants.
Side effects
Especially when taken in excess, CNS depressants can cause confusion and dizziness, and impair judgment, memory, intellectual performance, and motor coordination.
Interactions
CNS depressants should be used with other medications, such as antidepressant medications, only under a physician's supervision. Certain herbal remedies, such as Valerian and Kava, may dangerously exacerbate the effects of certain CNS depressants. Also, ingesting a combination of CNS depressants, such Valium and alcohol, for example, is not advised. When mixed together, CNS depressants tend to amplify each other's effects, which can cause severely reduced heart rate and even death.
You just have to know your own body and what you can tolerate. I remember I took flexeril with an opioid and I think some benadryl one night -- not smart for someone of my weight. I was actually scared to allow myself to go to sleep that night because I felt like I might never wake up but it sure felt good to deaden the pain for once.
I'm not trying to scare you -- just saying be careful. 
I've highlighted the key point near the end of this summary. SSRI's are not on this list but might be considered somewhat of a CNS depressant as is benadryl which is in tylenol PM.
Central Nervous System Depressants
Definition
Central nervous system (CNS) depressants are drugs that can be used to slow down brain activity.
Purpose
CNS depressants may be prescribed by a physician to treat anxiety, muscle tension, pain, insomnia, acute stress reactions, panic attacks, and seizure disorders. In higher doses, some CNS depressants may be used as general anesthetics.
Description
Throughout history, humans have sought relief from anxiety and insomnia by using substances that depress brain activity and induce a drowsy or calming effect. CNS depressants include a wide range of drugs such as alcohol, narcotics, barbiturates (Amytal, Nembutal, Seconal), benzodiazepines (Ativan, Halcion, Librium, Valium, Xanax), chloral hydrate, and methaqualone (Quaaludes), as well as newer CNS depressants developed in the 1990s, such as Buspirone (Buspar) and Zolpidem (Ambien), which are thought to have the fewest side effects. Most CNS depressants activate a neurotransmitter called gamma-aminobutyric acid (GABA), which helps decrease brain activity. Street names for CNS depressants include Reds, Yellows, Blues, Ludes, Barbs, and Downers.
Precautions
Most CNS depressants have the potential to be physically and psychologically addictive. Alcohol is the most widely abused depressant. The body tends to develop tolerance for CNS depressants, and larger doses are needed to achieve the same effects. Withdrawal from some CNS depressants can be uncomfortable; for example, withdrawal from a depressant treating insomnia or anxiety can cause rebound insomnia or anxiety as the brain's activity bounces back after being suppressed. In some cases withdrawal can result in lifethreatening seizures. Generally, depressant withdrawal should be undertaken under a physician's supervision. Many physicians will reduce the depressant dosage gradually, to give the body time to adjust. Certain CNS depressants such as barbiturates are easy to overdose on, since there is a relatively small difference between the optimal dose and an overdose. A small miscalculation can lead to coma, slowed breathing, and death. CNS depressants should be administered to elderly individuals with care, as these individuals have a reduced ability to metabolize CNS depressants.
Side effects
Especially when taken in excess, CNS depressants can cause confusion and dizziness, and impair judgment, memory, intellectual performance, and motor coordination.
Interactions
CNS depressants should be used with other medications, such as antidepressant medications, only under a physician's supervision. Certain herbal remedies, such as Valerian and Kava, may dangerously exacerbate the effects of certain CNS depressants. Also, ingesting a combination of CNS depressants, such Valium and alcohol, for example, is not advised. When mixed together, CNS depressants tend to amplify each other's effects, which can cause severely reduced heart rate and even death.
You just have to know your own body and what you can tolerate. I remember I took flexeril with an opioid and I think some benadryl one night -- not smart for someone of my weight. I was actually scared to allow myself to go to sleep that night because I felt like I might never wake up but it sure felt good to deaden the pain for once.
I'm not trying to scare you -- just saying be careful. PNE since 2002. Started from weightlifting. PNE surgery from Dr. Bautrant, Oct 2004. Pain now is usually a 0 and I can sit for hours on certain chairs. No longer take medication for PNE. Can work full time and do "The Firm" exercise program. 99% cured from PGAD. PNE surgery was right for me but it might not be for you. Do your research.